“Diseases like Alzheimer’s happen in two phases” – Futurity.org

Degenerative diseases happen in two distinct phases, according to new research.

degenerative-disease-alzheimers-parkinsons-phases-1600“‘The two phases of degeneration haven’t been previously recognized, so it hasn’t been understood, clinically, that you have two different populations of patients,’ says James McNew.” – (Credit: Leo Reynolds/Flickr)

Posted by Jade Boyd-Rice

“The researchers conducted countless experiments over more than a decade, and they’ve summarized all they’ve learned in a simple diagram they hope may change how doctors perceive and treat degenerative diseases as varied as Alzheimer’s, Parkinson’s, and muscle atrophy.

“The study in Molecular Psychiatry proposes that very different activities of protein signaling pathways that regulate basic cell functions mark the two phases.

“’We would like clinicians and other researchers to understand that the two phases of degeneration represent distinct entities, with distinct alterations in signaling pathways that have distinct effects on disease pathology,’ says Michael Stern, professor of biochemistry and cell biology in Rice University’s biosciences department.

“’In other words, we think that patients need to be treated differently depending on which phase they are in.'” – Continue reading this article at Futurity.org, click here.

 

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: